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  • 产品名称：Anti-DHTKD1 antibody (1-280) (STJ110667)

  • 产品型号：STJ110667
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DHTKD1 antibody (1-280) (STJ110667)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DHTKD1 (1-280) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DHTKD1
Gene ID: 55526
Uniprot ID: DHTK1_HUMAN
Immunogen Region: 1-280
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DHTKD1 (NP_061176.3).
Immunogen Sequence: MASATAAAARRGLGRALPLL WRGYQTERGVYGYRPRKPES REPQGALERPPVDHGLARLV TVYCEHGHKAAKINPLFTGQ ALLENVPEIQALVQTLQGPF HTAGLLNMGKEEASLEEVLV YLNQIYCGQISIETSQLQSQ DEKDWFAKRFEELQKETFTT EERKHLSKLMLESQEFDHFL ATKFSTVKRYGGEGAESMMG FFHELLKMSAYSGITDVIIG MPHRGRLNLLTGLLQFPPE
Function 2-oxoadipate dehydrogenase (E1a) component of the 2-oxoadipate dehydrogenase complex (OADHC). Participates in the first step, rate limiting for the overall conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2) catalyzed by the whole OADHC. Catalyzes the irreversible decarboxylation of 2-oxoadipate via the thiamine diphosphate (ThDP) cofactor and subsequent transfer of the decarboxylated acyl intermediate on an oxidized dihydrolipoyl group that is covalently amidated to the E2 enzyme (dihydrolipoyllysine-residue succinyltransferase or DLST) (Probable). Can catalyze the decarboxylation of 2-oxoglutarate in vitro, but at a much lower rate than 2-oxoadipate. Responsible for the last step of L-lysine, L-hydroxylysine and L-tryptophan catabolism with the common product being 2-oxoadipate (Probable).
Protein Name 2-Oxoadipate Dehydrogenase Complex Component E1
E1a
Oadc-E1
Oadh-E1
2-Oxoadipate Dehydrogenase - Mitochondrial
Alpha-Ketoadipate Dehydrogenase
Alpha-Kadh-E1
Dehydrogenase E1 And Transketolase Domain-Containing Protein 1
Probable 2-Oxoglutarate Dehydrogenase E1 Component Dhktd1 - Mitochondrial
Database Links Reactome: R-HSA-389661
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-2-Oxoadipate Dehydrogenase Complex Component E1 antibody
Anti-E1a antibody
Anti-Oadc-E1 antibody
Anti-Oadh-E1 antibody
Anti-2-Oxoadipate Dehydrogenase - Mitochondrial antibody
Anti-Alpha-Ketoadipate Dehydrogenase antibody
Anti-Alpha-Kadh-E1 antibody
Anti-Dehydrogenase E1 And Transketolase Domain-Containing Protein 1 antibody
Anti-Probable 2-Oxoglutarate Dehydrogenase E1 Component Dhktd1 - Mitochondrial antibody
Anti-DHTKD1 antibody
Anti-KIAA1630 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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