产品详情
简单介绍:
Mouse HADHb (Hydroxyacyl Coenzyme A Dehydrogenase Beta) Sandwich ELISA Kit Ready-To-Use (STJE0015767)
详情介绍:
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.115ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This HADHb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Hadhb |
| Gene ID: | 231086 |
| Uniprot ID: | ECHB_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Acetylation of Lys-202 is observed in liver mitochondria from fasted mice but not from fed mice. |
| Function | Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity. |
| Protein Name | Trifunctional Enzyme Subunit Beta - Mitochondrial Tp-Beta Includes - 3-Ketoacyl-Coa Thiolase Acetyl-Coa Acyltransferase Beta-Ketothiolase |
| Database Links | Reactome: R-MMU-1482798 Reactome: -MMU-77285 Reactome: -MMU-77305 Reactome: -MMU-77310 Reactome: -MMU-77346 Reactome: -MMU-77348 Reactome: -MMU-77350 |
| Cellular Localisation | Mitochondrion Mitochondrion Inner Membrane Mitochondrion Outer Membrane Endoplasmic Reticulum Protein Stability And Association With Membranes Require Hadha |
| Alternative ELISA Names | Trifunctional Enzyme Subunit Beta - Mitochondrial ELISA kit Tp-Beta Includes - 3-Ketoacyl-Coa Thiolase ELISA kit Acetyl-Coa Acyltransferase ELISA kit Beta-Ketothiolase ELISA kit Hadhb ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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