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  • 产品名称：Mouse HEXb (Hexosaminidase B Beta) Sandwich ELISA Kit Ready-To-Use (STJE0015822)

  • 产品型号：STJE0015822
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse HEXb (Hexosaminidase B Beta) Sandwich ELISA Kit Ready-To-Use (STJE0015822)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.118ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This HEXb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Hexb
Gene ID: 15212
Uniprot ID: HEXB_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida.
Protein Name Beta-Hexosaminidase Subunit Beta
Beta-N-Acetylhexosaminidase Subunit Beta
Hexosaminidase Subunit B
N-Acetyl-Beta-Glucosaminidase Subunit Beta
Database Links Reactome: R-MMU-1660662
Reactome: -MMU-2022857
Reactome: -MMU-2024101
Reactome: -MMU-2160916
Reactome: -MMU-6798695
Cellular Localisation Lysosome
Cytoplasmic Vesicle
Secretory Vesicle
Cortical Granule
In Oocytes
The Enzyme Is Released From Cortical Granules After Fertilization
Alternative ELISA Names Beta-Hexosaminidase Subunit Beta ELISA kit
Beta-N-Acetylhexosaminidase Subunit Beta ELISA kit
Hexosaminidase Subunit B ELISA kit
N-Acetyl-Beta-Glucosaminidase Subunit Beta ELISA kit
Hexb ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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