产品详情
简单介绍:
Anti-DNAJA1 antibody (178-397) (STJ113207)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DNAJA1 (178-397) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:5000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DNAJA1 |
Gene ID: | 3301 |
Uniprot ID: | DNJA1_HUMAN |
Immunogen Region: | 178-397 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 178-397 of human DNAJA1 (NP_001530.1). |
Immunogen Sequence: | MECQGHGERISPKDRCKSCN GRKIVREKKILEVHIDKGMK DGQKITFHGEGDQEPGLEPG DIIIVLDQKDHAVFTRRGED LFMCMDIQLVEALCGFQKPI STLDNRTIVITSHPGQIVKH GDIKCVLNEGMPIYRRPYEK GRLIIEFKVNFPENGFLSPD KLSLLEKLLPERKEVEETDE MDQVELVDFDPNQERRRHYN GEAYEDDEHHPRGGVQCQTS |
Tissue Specificity | Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver. |
Function | Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV. |
Protein Name | Dnaj Homolog Subfamily A Member 1 Dnaj Protein Homolog 2 Hsdj Heat Shock 40 Kda Protein 4 Heat Shock Protein J2 Hsj-2 Human Dnaj Protein 2 Hdj-2 |
Database Links | Reactome: R-HSA-3371497 |
Cellular Localisation | Membrane Lipid-Anchor Cytoplasm Microsome Nucleus Perinuclear Region Mitochondrion Primarily Associated With Microsomes A Minor Proportion Is Associated With Mitochondria Primarily Cytoplasmic A Minor Proportion Is Associated With Nuclei |
Alternative Antibody Names | Anti-Dnaj Homolog Subfamily A Member 1 antibody Anti-Dnaj Protein Homolog 2 antibody Anti-Hsdj antibody Anti-Heat Shock 40 Kda Protein 4 antibody Anti-Heat Shock Protein J2 antibody Anti-Hsj-2 antibody Anti-Human Dnaj Protein 2 antibody Anti-Hdj-2 antibody Anti-DNAJA1 antibody Anti-DNAJ2 antibody Anti-HDJ2 antibody Anti-HSJ2 antibody Anti-HSPF4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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