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  • 产品名称：Anti-DNAJB9 antibody (24-223) (STJ29630)

  • 产品型号：STJ29630
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DNAJB9 antibody (24-223) (STJ29630)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNAJB9 (24-223) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DNAJB9
Gene ID: 4189
Uniprot ID: DNJB9_HUMAN
Immunogen Region: 24-223
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-223 of human DNAJB9 (NP_036460.1).
Immunogen Sequence: SKSYYDILGVPKSASERQIK KAFHKLAMKYHPDKNKSPDA EAKFREIAEAYETLSDANRR KEYDTLGHSAFTSGKGQRGS GSSFEQSFNFNFDDLFKDFG FFGQNQNTGSKKRFENHFQT RQDGGSSRQRHHFQEFSFGG GLFDDMFEDMEKMFSFSGFD STNQHTVQTENRFHGSSKHC RTVTQRRGNMVTTYTDCSGQ
Tissue Specificity Widely expressed. Expressed at highest level in the liver, placenta and kidney.
Function Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production.
Protein Name Dnaj Homolog Subfamily B Member 9
Endoplasmic Reticulum Dna J Domain-Containing Protein 4
Er-Resident Protein Erdj4
Erdj4
Microvascular Endothelial Differentiation Gene 1 Protein
Mdg-1
Database Links Reactome: R-HSA-381038
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Antibody Names Anti-Dnaj Homolog Subfamily B Member 9 antibody
Anti-Endoplasmic Reticulum Dna J Domain-Containing Protein 4 antibody
Anti-Er-Resident Protein Erdj4 antibody
Anti-Erdj4 antibody
Anti-Microvascular Endothelial Differentiation Gene 1 Protein antibody
Anti-Mdg-1 antibody
Anti-DNAJB9 antibody
Anti-MDG1 antibody
Anti-UNQ743 antibody
Anti-PRO1471 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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