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  • 产品名称：Mouse HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015983)

  • 产品型号：STJE0015983
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015983)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 26.6pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This HTR2C Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Htr2c
Gene ID: 15560
Uniprot ID: 5HT2C_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Detected in brain cortex, hypothalamus, brainstem and arcuate nucleus. Detected in the paraventricular nucleus of the hypothalamus.
Post Translational Modifications N-glycosylated.
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and feeding behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.
Protein Name 5-Hydroxytryptamine Receptor 2c
5-Ht-2c
5-Ht2c
5-Htr2c
5-Hydroxytryptamine Receptor 1c
5-Ht-1c
5-Ht1c
Serotonin Receptor 2c
Database Links Reactome: R-MMU-390666
Reactome: -MMU-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names 5-Hydroxytryptamine Receptor 2c ELISA kit
5-Ht-2c ELISA kit
5-Ht2c ELISA kit
5-Htr2c ELISA kit
5-Hydroxytryptamine Receptor 1c ELISA kit
5-Ht-1c ELISA kit
5-Ht1c ELISA kit
Serotonin Receptor 2c ELISA kit
Htr2c ELISA kit
5ht1c ELISA kit
Htr1c ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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