产品详情
简单介绍:
Mouse IQGAP1 (IQ Motif Containing GTPase Activating Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0016429)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.136ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This IQGAP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Iqgap1 |
Gene ID: | 29875 |
Uniprot ID: | IQGA1_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in the kidney (at protein level). |
Post Translational Modifications | |
Function | Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest. |
Protein Name | Ras Gtpase-Activating-Like Protein Iqgap1 |
Database Links | Reactome: R-MMU-373753 Reactome: -MMU-5626467 Reactome: -MMU-5674135 Reactome: -MMU-6798695 Reactome: -MMU-8980692 Reactome: -MMU-9013106 Reactome: -MMU-9013149 Reactome: -MMU-9013404 Reactome: -MMU-9013406 Reactome: -MMU-9013420 Reactome: -MMU-9013424 |
Cellular Localisation | Cell Membrane Nucleus Cytoplasm Apical Cell Membrane Basolateral Cell Membrane Subcellular Distribution Is Regulated By The Cell Cycle Nuclear Levels Increase At G1/S Phase |
Alternative ELISA Names | Ras Gtpase-Activating-Like Protein Iqgap1 ELISA kit Iqgap1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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