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  • 产品名称：Mouse LPCAT1 (Lysophosphatidylcholine Acyltransferase 1) Sandwich ELISA Kit (STJE0010395)

  • 产品型号：STJE0010395
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse LPCAT1 (Lysophosphatidylcholine Acyltransferase 1) Sandwich ELISA Kit (STJE0010395)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This LPCAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Lpcat1
Gene ID: 210992
Uniprot ID: PCAT1_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Predominantly expressed in lung where it is enriched in alveolar type II cells. Expressed at lower levels in spleen and brain. Also detected in erythroleukemic cells and reticulocytes. Weakly or not expressed in other tissues.
Post Translational Modifications
Function Exhibits both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Involved in the regulation of lipid droplet number and size.
Protein Name Lysophosphatidylcholine Acyltransferase 1
Lpc Acyltransferase 1
Lpcat-1
Lysopc Acyltransferase 1
Mlpcat1
1-Acylglycerol-3-Phosphate O-Acyltransferase
1-Acylglycerophosphocholine O-Acyltransferase
1-Alkenylglycerophosphocholine O-Acyltransferase
1-Alkylglycerophosphocholine O-Acetyltransferase
Acetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase
Acetyl-Coa -Lyso-Paf Acetyltransferase
Lyso-Paf Acetyltransferase
Lysopafat
Acyltransferase-Like 2
Database Links Reactome: R-MMU-1482788
Reactome: -MMU-1482925
Reactome: -MMU-1483166
Reactome: -MMU-1483191
Reactome: -MMU-6798695
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Golgi Apparatus Membrane
Cell Membrane
Lipid Droplet
May Adopt A Monotopic Topology When Embedded In The Lipid Monolayer Of The Lipid Droplet
With Both Termini Exposed To The Cytoplasm
Alternative ELISA Names Lysophosphatidylcholine Acyltransferase 1 ELISA kit
Lpc Acyltransferase 1 ELISA kit
Lpcat-1 ELISA kit
Lysopc Acyltransferase 1 ELISA kit
Mlpcat1 ELISA kit
1-Acylglycerol-3-Phosphate O-Acyltransferase ELISA kit
1-Acylglycerophosphocholine O-Acyltransferase ELISA kit
1-Alkenylglycerophosphocholine O-Acyltransferase ELISA kit
1-Alkylglycerophosphocholine O-Acetyltransferase ELISA kit
Acetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase ELISA kit
Acetyl-Coa -Lyso-Paf Acetyltransferase ELISA kit
Lyso-Paf Acetyltransferase ELISA kit
Lysopafat ELISA kit
Acyltransferase-Like 2 ELISA kit
Lpcat1 ELISA kit
Aytl2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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