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  • 产品名称：Anti-ECHS1 antibody (STJA0006828)

  • 产品型号：STJA0006828
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ECHS1 antibody (STJA0006828)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Enoyl-CoA hydratase, mitochondrial is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ECHS1
Gene ID: 1892
Uniprot ID: ECHM_HUMAN
Specificity: This antibody detects endogenous levels of ECHS1 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human ECHS1
Function Converts unsaturated trans-2-enoyl-CoA species ((2E)-enoyl-CoA) to the corresponding (3S)-3hydroxyacyl-CoA species through addition of a water molecule to the double bond. Catalyzes the hydration of medium- and short-chained fatty enoyl-CoA thioesters from 4 carbons long (C4) up to C16. Has high substrate specificity for crotonyl-CoA ((2E)-butenoyl-CoA) and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA) and methacrylyl-CoA ((2E)-2-methylpropenoyl-CoA). Can bind tiglyl-CoA (2-methylcrotonoyl-CoA), but hydrates only a small amount of this substrate. Plays a key role in the beta-oxidation spiral of short- and medium-chain fatty acid oxidation. At a lower rate than the hydratase reaction, catalyzes the isomerase reaction of trans-3-enoyl-CoA species (such as (3E)-hexenoyl-CoA) to trans-2-enoyl-CoA species (such as (2E)-hexenoyl-CoA), which are subsequently hydrated to 3(S)-3-hydroxyacyl-CoA species (such as (3S)-hydroxyhexanoyl-CoA).
Protein Name Enoyl-Coa Hydratase - Mitochondrial
Mech
Mech1
Enoyl-Coa Hydratase 1
Echs1
Short-Chain Enoyl-Coa Hydratase
Sceh
Database Links Reactome: R-HSA-70895
Reactome: R-HSA-77310
Reactome: R-HSA-77346
Reactome: R-HSA-77348
Reactome: R-HSA-77350
Reactome: R-HSA-77352
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Enoyl-Coa Hydratase - Mitochondrial antibody
Anti-Mech antibody
Anti-Mech1 antibody
Anti-Enoyl-Coa Hydratase 1 antibody
Anti-Echs1 antibody
Anti-Short-Chain Enoyl-Coa Hydratase antibody
Anti-Sceh antibody
Anti-ECHS1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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