产品详情
简单介绍:
Mouse MCAM (Melanoma Cell Adhesion Molecule) Sandwich ELISA Kit Ready-To-Use (STJE0016903)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.234ng/mL |
Detection Limit: | 0.625-40ng/mL |
Short Description: | This MCAM Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Mcam |
Gene ID: | 84004 |
Uniprot ID: | MUC18_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | Detected in melanoma cell lines. |
Post Translational Modifications | |
Function | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
Protein Name | Cell Surface Glycoprotein Muc18 Gicerin Melanoma Cell Adhesion Molecule Melanoma-Associated Antigen Muc18 Cd Antigen Cd146 |
Database Links | Reactome: R-MMU-8980692 Reactome: -MMU-9013026 Reactome: -MMU-9013106 Reactome: -MMU-9013149 Reactome: -MMU-9013404 Reactome: -MMU-9013405 Reactome: -MMU-9013408 Reactome: -MMU-9013423 Reactome: -MMU-9035034 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative ELISA Names | Cell Surface Glycoprotein Muc18 ELISA kit Gicerin ELISA kit Melanoma Cell Adhesion Molecule ELISA kit Melanoma-Associated Antigen Muc18 ELISA kit Cd Antigen Cd146 ELISA kit Mcam ELISA kit Muc18 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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