产品详情
简单介绍:
Mouse NRG4 (Neuregulin 4) Sandwich ELISA Kit (STJE0011085)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.128ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This NRG4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Nrg4 |
Gene ID: | 83961 |
Uniprot ID: | NRG4_MOUSE |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Highly expressed in pancreas.weakly expressed in muscle. |
Post Translational Modifications | Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form. Extensive glycosylation precedes the proteolytic cleavage. |
Function | Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. |
Protein Name | Pro-Neuregulin-4 - Membrane-Bound Isoform Pro-Nrg4 Cleaved Into - Neuregulin-4 Nrg-4 |
Database Links | |
Cellular Localisation | Pro-Neuregulin-4 Membrane-Bound Isoform: Cell Membrane Single-Pass Type I Membrane Protein Does Not Seem To Be Active Neuregulin-4: Secreted |
Alternative ELISA Names | Pro-Neuregulin-4 - Membrane-Bound Isoform ELISA kit Pro-Nrg4 Cleaved Into - Neuregulin-4 ELISA kit Nrg-4 ELISA kit Nrg4 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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