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  • 产品名称：Anti-EIF4G1 antibody (1074-1123 aa) (STJ92883)

  • 产品型号：STJ92883
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-EIF4G1 antibody (1074-1123 aa) (STJ92883)
详情介绍：
Host: Rabbit
Applications: IHC/IF/WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Eukaryotic translation initiation factor 4 gamma 1 (1074-1123 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EIF4G1
Gene ID: 1981
Uniprot ID: IF4G1_HUMAN
Immunogen Region: 1074-1123 aa
Specificity: eIF4G Polyclonal Antibody detects endogenous levels of eIF4G protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human eIF4G at the amino acid range 1074-1123
Function Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Exists in two complexes, either with EIF1 or with EIF4E (mutually exclusive). Together with EIF1, is required for leaky scanning, in particular for avoiding cap-proximal start codon. Together with EIF4E, antagonizes the scanning promoted by EIF1-EIF4G1 and locates the start codon (through a TISU element) without scanning. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation.
Protein Name Eukaryotic Translation Initiation Factor 4 Gamma 1
Eif-4-Gamma 1
Eif-4g 1
Eif-4g1
P220
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-156827
Reactome: R-HSA-166208
Reactome: R-HSA-429947
Reactome: R-HSA-450408
Reactome: R-HSA-72649
Reactome: R-HSA-72662
Reactome: R-HSA-72702
Reactome: R-HSA-72706
Reactome: R-HSA-9010553
Reactome: R-HSA-975956
Reactome: R-HSA-975957
Cellular Localisation Cytoplasm
Nucleus
Stress Granule
Alternative Antibody Names Anti-Eukaryotic Translation Initiation Factor 4 Gamma 1 antibody
Anti-Eif-4-Gamma 1 antibody
Anti-Eif-4g 1 antibody
Anti-Eif-4g1 antibody
Anti-P220 antibody
Anti-EIF4G1 antibody
Anti-EIF4F antibody
Anti-EIF4G antibody
Anti-EIF4GI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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