产品详情
简单介绍:
Anti-ELOVL1 antibody (148-198) (STJ500870)
详情介绍:
Host: | Rabbit |
Applications: | ELISA/IHC/IP/WB |
Reactivity: | Human/Monkey/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ELOVL1 (148-198) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.5 µg/µl |
Dilution Range: | WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | ELOVL1 |
Gene ID: | 64834 |
Uniprot ID: | ELOV1_HUMAN |
Immunogen Region: | 148-198 |
Immunogen: | Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1. |
Tissue Specificity | Ubiquitous. |
Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. |
Protein Name | Elongation Of Very Long Chain Fatty Acids Protein 1 3-Keto Acyl-Coa Synthase Elovl1 Elovl Fatty Acid Elongase 1 Elovl Fa Elongase 1 Very Long Chain 3-Ketoacyl-Coa Synthase 1 Very Long Chain 3-Oxoacyl-Coa Synthase 1 |
Database Links | Reactome: R-HSA-2046105 Reactome: R-HSA-2046106 Reactome: R-HSA-75876 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Elongation Of Very Long Chain Fatty Acids Protein 1 antibody Anti-3-Keto Acyl-Coa Synthase Elovl1 antibody Anti-Elovl Fatty Acid Elongase 1 antibody Anti-Elovl Fa Elongase 1 antibody Anti-Very Long Chain 3-Ketoacyl-Coa Synthase 1 antibody Anti-Very Long Chain 3-Oxoacyl-Coa Synthase 1 antibody Anti-ELOVL1 antibody Anti-SSC1 antibody Anti-CGI-88 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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