产品详情
简单介绍:
Mouse SCGN (Secretagogin) Sandwich ELISA Kit Ready-To-Use (STJE0018425)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 31pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description: | This SCGN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Stmn2 |
Gene ID: | 20257 |
Uniprot ID: | STMN2_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Neuron specific. |
Post Translational Modifications | Sumoylated. Phosphorylated mostly by MAPK8, but also by MAPK9 and MAPK10 in the developing brain cortex. N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15. |
Function | Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. |
Protein Name | Stathmin-2 Superior Cervical Ganglion-10 Protein Protein Scg10 |
Database Links | Reactome: R-MMU-9696273 |
Cellular Localisation | Cytoplasm Perinuclear Region Cell Projection Growth Cone Axon Membrane Peripheral Membrane Protein Cytoplasmic Side Endosome Golgi Apparatus Lamellipodium Colocalized With Cib1 In Neurites Of Developing Hippocampal Primary Neurons Colocalized With Cib1 In The Cell Body Neuritis Growth Cones Of Neurons And In Neurites Of Developing Hippocampal Primary Neurons Colocalized With Cib1 To The Leading Edge Of Lamellipodia Associated With Punctate Structures In The Perinuclear Cytoplasm Axons And Growth Cones Of Developing Neurons Exists In Both Soluble And Membrane-Bound Forms In The Developing Brain Mostly Cytosolic |
Alternative ELISA Names | Stathmin-2 ELISA kit Superior Cervical Ganglion-10 Protein ELISA kit Protein Scg10 ELISA kit Stmn2 ELISA kit Scg10 ELISA kit Scgn10 ELISA kit Stmb2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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