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  • 产品名称：Anti-ERLIN2 antibody (239-289 aa) (STJ195613)

  • 产品型号：STJ195613
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ERLIN2 antibody (239-289 aa) (STJ195613)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Erlin-2 (239-289 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERLIN2
Gene ID: 11160
Uniprot ID: ERLN2_HUMAN
Immunogen Region: 239-289 aa
Specificity: This antibody detects endogenous levels of ERLN2 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human ERLN2 at the amino acid range 239-289
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.
Protein Name Erlin-2
Endoplasmic Reticulum Lipid Raft-Associated Protein 2
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2
Spfh Domain-Containing Protein 2
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5655302
Reactome: R-HSA-5678895
Reactome: R-HSA-8853336
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Erlin-2 antibody
Anti-Endoplasmic Reticulum Lipid Raft-Associated Protein 2 antibody
Anti-Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2 antibody
Anti-Spfh Domain-Containing Protein 2 antibody
Anti-ERLIN2 antibody
Anti-C8orf2 antibody
Anti-SPFH2 antibody
Anti-UNQ2441 antibody
Anti-PRO5003 antibody
Anti-PRO9924 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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