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  • 产品名称：Mouse VCL (Vinculin) Sandwich ELISA Kit Ready-To-Use (STJE0019375)

  • 产品型号：STJE0019375
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse VCL (Vinculin) Sandwich ELISA Kit Ready-To-Use (STJE0019375)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.105ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This VCL Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Vcl
Gene ID: 22330
Uniprot ID: VINC_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated.on serines, threonines and tyrosines. Phosphorylation on Tyr-1065 in activated platelets affects head-tail interactions and cell spreading but has no effect on actin binding nor on localization to focal adhesion plaques. Acetylated.mainly by myristic acid but also by a small amount of palmitic acid.
Function Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Protein Name Vinculin
Metavinculin
Database Links Reactome: R-MMU-114608
Reactome: -MMU-445355
Reactome: -MMU-5674135
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cell Junction
Adherens Junction
Focal Adhesion
Cytoplasm
Cytoskeleton
Sarcolemma
Cell Projection
Podosome
Recruitment To Cell-Cell Junctions Occurs In A Myosin Ii-Dependent Manner
Interaction With Ctnnb1 Is Necessary For Its Localization To The Cell-Cell Junctions
Alternative ELISA Names Vinculin ELISA kit
Metavinculin ELISA kit
Vcl ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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