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  • 产品名称：Anti-FBLIM1 antibody (157-207 aa) (STJ195810)

  • 产品型号：STJ195810
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-FBLIM1 antibody (157-207 aa) (STJ195810)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Filamin-binding LIM protein 1 (157-207 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FBLIM1
Gene ID: 54751
Uniprot ID: FBLI1_HUMAN
Immunogen Region: 157-207 aa
Specificity: This antibody detects endogenous levels of FBLI1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human FBLI1 at the amino acid range 157-207
Function Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Protein Name Filamin-Binding Lim Protein 1
Fblp-1
Migfilin
Mitogen-Inducible 2-Interacting Protein
Mig2-Interacting Protein
Database Links Reactome: R-HSA-446353
Cellular Localisation Cell Junction
Focal Adhesion
Cytoplasm
Cytoskeleton
Stress Fiber
Associated With Actin Stress Fiber At Cell-Ecm Focal Adhesion Sites
Isoform 1 And Isoform 3 Are Recruited And Localized At Actin Stress Fibers And Clustered At Cell-Emc Adhesion Sites Through Interaction With Fermt2
Isoform 2 Is Localized At Actin Stress Fibers
Alternative Antibody Names Anti-Filamin-Binding Lim Protein 1 antibody
Anti-Fblp-1 antibody
Anti-Migfilin antibody
Anti-Mitogen-Inducible 2-Interacting Protein antibody
Anti-Mig2-Interacting Protein antibody
Anti-FBLIM1 antibody
Anti-FBLP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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