产品详情
简单介绍:
Anti-FBLN5 antibody [3F10A5/3F8A12] (STJ98074)
详情介绍:
Host: | Mouse |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Fibulin-5 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Monoclonal |
Clone ID: | 3F10A5/3F8A12 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC 1:200-1:1000 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FBLN5 |
Gene ID: | 10516 |
Uniprot ID: | FBLN5_HUMAN |
Specificity: | Fibulin-5 Monoclonal Antibody detects endogenous levels of Fibulin-5 protein. |
Immunogen: | Purified recombinant fragment of Fibulin-5 expressed in E. Coli. |
Post Translational Modifications | N-glycosylated. |
Function | Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. |
Protein Name | Fibulin-5 Fibl-5 Developmental Arteries And Neural Crest Egf-Like Protein Dance Urine P50 Protein Up50 |
Database Links | Reactome: R-HSA-1566948 Reactome: R-HSA-2129379 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix Co-Localizes With Eln In Elastic Fibers |
Alternative Antibody Names | Anti-Fibulin-5 antibody Anti-Fibl-5 antibody Anti-Developmental Arteries And Neural Crest Egf-Like Protein antibody Anti-Dance antibody Anti-Urine P50 Protein antibody Anti-Up50 antibody Anti-FBLN5 antibody Anti-DANCE antibody Anti-UNQ184 antibody Anti-PRO210 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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