产品详情
查看大图

  • 产品名称：Anti-FBN2 antibody (2733-2912) (STJ113641)

  • 产品型号：STJ113641
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-FBN2 antibody (2733-2912) (STJ113641)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FBN2 (2733-2912) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FBN2
Gene ID: 2201
Uniprot ID: FBN2_HUMAN
Immunogen Region: 2733-2912
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2733-2912 of human FBN2 (NP_001990.2).
Immunogen Sequence: CVSGMGFNKGQYLSLDTEVD EENALSPEACYECKINGYSK KDSRQKRSIHEPDPTAVEQI SLESVDMDSPVNMKFNLSHL GSKEHILELRPAIQPLNNHI RYVISQGNDDSVFRIHQRNG LSYLHTAKKKLMPGTYTLEI TSIPLYKKKELKKLEESNED DYLLGELGEALRMRLQIQLY
Tissue Specificity Almost exclusively expressed in placenta. Expressed at much lower level in other tissues. Expressed in fetal eye (18 weeks)in the retinal pigment epithelium (RPE), the choroid, Bruch's membrane and in the sclera. Not expressed in the neural retina. Placensin: Present at high level in cytotrophoblasts as compared with syncytiotrophoblasts at 8-9 weeks of pregnancy (at protein level). Levels in the serum increase during pregnancy (at protein level).
Post Translational Modifications Placensin: N-glycosylated. O-glycosylated on serine residues by POGLUT2 and POGLUT3.
Function Fibrillin-2: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Placensin: Hormone secreted by trophoblasts that promotes trophoblast invasiveness. Has glucogenic activity: is able to increase plasma glucose levels.
Protein Name Fibrillin-2 Cleaved Into - Placensin
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-1566948
Reactome: R-HSA-2129379
Cellular Localisation Secreted
Fibrillin-2 And Placensin Chains Are Still Linked Together During The Secretion From Cells
But Are Subsequently Separated By Furin
Fibrillin-2: Secreted
Extracellular Space
Extracellular Matrix
Placensin: Secreted
Secreted By Placental Cells
Alternative Antibody Names Anti-Fibrillin-2 Cleaved Into - Placensin antibody
Anti-FBN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号