产品详情
查看大图

  • 产品名称：Mouse VGLUT1 (Vesicular Glutamate Transporter 1) Sandwich ELISA Kit (STJE0013035)

  • 产品型号：STJE0013035
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Mouse VGLUT1 (Vesicular Glutamate Transporter 1) Sandwich ELISA Kit (STJE0013035)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.124ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This VGLUT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Slc17a7
Gene ID: 72961
Uniprot ID: VGLU1_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in hippocampus (at protein level). Expressed in the molecular layer of the cerebellum and in retina.
Post Translational Modifications
Function Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate. At the synaptic vesicle membrane, mainly functions as an uniporter which transports preferentially L-glutamate but also phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane. In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification. Moreover, may function as a K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake. The vesicular K(+)/H(+) antiport activity is electroneutral. At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation. The symporter activity is driven by an inside negative membrane potential and is electrogenic. Is necessary for synaptic signaling of visual-evoked responses from photoreceptors.
Protein Name Vesicular Glutamate Transporter 1
Vglut1
Brain-Specific Na(+-Dependent Inorganic Phosphate Cotransporter
Solute Carrier Family 17 Member 7
Database Links Reactome: R-MMU-210500
Reactome: -MMU-428643
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Cell Membrane
Multi-Pass Membrane Protein
Synapse
Synaptosome
Alternative ELISA Names Vesicular Glutamate Transporter 1 ELISA kit
Vglut1 ELISA kit
Brain-Specific Na(+-Dependent Inorganic Phosphate Cotransporter ELISA kit
Solute Carrier Family 17 Member 7 ELISA kit
Slc17a7 ELISA kit
Bnpi ELISA kit
Vglut1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号