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  • 产品名称：Anti-CDCP1 antibody (241-290 aa) (STJ96656)

  • 产品型号：STJ96656
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CDCP1 antibody (241-290 aa) (STJ96656)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CUB domain-containing protein 1 (241-290 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDCP1
Gene ID: 64866
Uniprot ID: CDCP1_HUMAN
Immunogen Region: 241-290 aa
Specificity: CDCP1 Polyclonal Antibody detects endogenous levels of CDCP1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CDCP1 at the amino acid range 241-290
Post Translational Modifications Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5. N-glycosylated. A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.
Function May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Protein Name Cub Domain-Containing Protein 1
Membrane Glycoprotein Gp140
Subtractive Immunization M Plus Hep3-Associated 135 Kda Protein
Sima135
Transmembrane And Associated With Src Kinases
Cd Antigen Cd318
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Membrane Protein
Shedding May Also Lead To A Soluble Peptide
Isoform 3: Secreted
Alternative Antibody Names Anti-Cub Domain-Containing Protein 1 antibody
Anti-Membrane Glycoprotein Gp140 antibody
Anti-Subtractive Immunization M Plus Hep3-Associated 135 Kda Protein antibody
Anti-Sima135 antibody
Anti-Transmembrane And Associated With Src Kinases antibody
Anti-Cd Antigen Cd318 antibody
Anti-CDCP1 antibody
Anti-TRASK antibody
Anti-UNQ2486 antibody
Anti-PRO5773 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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