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  • 产品名称：Mouse IP10 (Interferon Gamma Induced Protein 10kDa) Sandwich ELISA Kit Ready-To-Use (STJE0016422)

  • 产品型号：STJE0016422
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse IP10 (Interferon Gamma Induced Protein 10kDa) Sandwich ELISA Kit Ready-To-Use (STJE0016422)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 5.7pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This IP10 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Cxcl10
Gene ID: 15945
Uniprot ID: CXL10_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Expressed in the spleen, thymus, lymph nodes and liver. Expressed in astrocytes, microglia, and neurons.
Post Translational Modifications
Function Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects. Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites. Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization. In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation. Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization.
Protein Name C-X-C Motif Chemokine 10
10 Kda Interferon Gamma-Induced Protein
Gamma-Ip10
Ip-10
C7
Interferon-Gamma Induced Protein Crg-2
Small-Inducible Cytokine B10
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Cellular Localisation Secreted
Alternative ELISA Names C-X-C Motif Chemokine 10 ELISA kit
10 Kda Interferon Gamma-Induced Protein ELISA kit
Gamma-Ip10 ELISA kit
Ip-10 ELISA kit
C7 ELISA kit
Interferon-Gamma Induced Protein Crg-2 ELISA kit
Small-Inducible Cytokine B10 ELISA kit
Cxcl10 ELISA kit
Crg2 ELISA kit
Ifi10 ELISA kit
Inp10 ELISA kit
Scyb10 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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