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  • 产品名称：Mouse SPI1 (Spleen Focus Forming Virus Proviral Integration Oncogene) Sandwich ELISA Kit Ready-To-Use (STJE0018695)

  • 产品型号：STJE0018695
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse SPI1 (Spleen Focus Forming Virus Proviral Integration Oncogene) Sandwich ELISA Kit Ready-To-Use (STJE0018695)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 31ng/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This SPI1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Spi1
Gene ID: 20375
Uniprot ID: SPI1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in spleen, thymus and bone-marrow macrophages.
Post Translational Modifications
Function Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions. Transcriptionally activates genes important for myeloid and lymphoid lineages, such as CSF1R. Transcriptional activation from certain promoters, possibly containing low affinity binding sites, is achieved cooperatively with other transcription factors. FCER1A transactivation is achieved in cooperation with GATA1. May be particularly important for the pro- to pre-B cell transition. Binds (via the ETS domain) onto the purine-rich DNA core sequence 5'-GAGGAA-3', also known as the PU-box. In vitro can bind RNA and interfere with pre-mRNA splicing.
Protein Name Transcription Factor Pu.1
31 Kda-Transforming Protein
Sffv Proviral Integration 1 Protein
Database Links
Cellular Localisation Nucleus
Alternative ELISA Names Transcription Factor Pu.1 ELISA kit
31 Kda-Transforming Protein ELISA kit
Sffv Proviral Integration 1 Protein ELISA kit
Spi1 ELISA kit
Sfpi-1 ELISA kit
Sfpi1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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