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  • 产品名称：Anti-FCGR3B antibody (1-233) (STJ115915)

  • 产品型号：STJ115915
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-FCGR3B antibody (1-233) (STJ115915)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FCGR3B (1-233) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCGR3B
Gene ID: 2215
Uniprot ID: FCG3B_HUMAN
Immunogen Region: 1-233
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).
Immunogen Sequence: MWQLLLPTALLLLVSAGMRT EDLPKAVVFLEPQWYSVLEK DSVTLKCQGAYSPEDNSTQW FHNENLISSQASSYFIDAAT VNDSGEYRCQTNLSTLSDPV QLEVHIGWLLLQAPRWVFKE EDPIHLRCHSWKNTALHKVT YLQNGKDRKYFHHNSDFHIP KATLKDSGSYFCRGLVGSKN VSSETVNITITQGLAVSTIS SFSPPGYQVSFCLVMVLLFA VDTGLYFSVKTNI
Tissue Specificity Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.
Post Translational Modifications Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B
Fc-Gamma Riii-Beta
Cd16-I
Fc-Gamma Riii
Fc-Gamma Riiib
Fcriii
Fcriiib
Fcr-10
Igg Fc Receptor Iii-1
Cd Antigen Cd16b
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Secreted After Cleavage
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B antibody
Anti-Fc-Gamma Riii-Beta antibody
Anti-Cd16-I antibody
Anti-Fc-Gamma Riii antibody
Anti-Fc-Gamma Riiib antibody
Anti-Fcriii antibody
Anti-Fcriiib antibody
Anti-Fcr-10 antibody
Anti-Igg Fc Receptor Iii-1 antibody
Anti-Cd Antigen Cd16b antibody
Anti-FCGR3B antibody
Anti-CD16B antibody
Anti-FCG3 antibody
Anti-FCGR3 antibody
Anti-IGFR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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