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  • 产品名称：Anti-FCHO1 antibody (STJA0008629)

  • 产品型号：STJA0008629
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-FCHO1 antibody (STJA0008629)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-F-BAR domain only protein 1 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCHO1
Gene ID: 23149
Uniprot ID: FCHO1_HUMAN
Specificity: This antibody detects endogenous levels of FCHO1 at Human, Mouse
Immunogen: Synthesized peptide derived from human FCHO1
Function Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. Involved in the regulation of T-cell poliferation and activation. Affects TCR clustering upon receptor triggering and modulates its internalisation, playing a role in TCR-dependent T-cell activation.
Protein Name F-Bar Domain Only Protein 1
Database Links Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Membrane
Clathrin-Coated Pit
Peripheral Membrane Protein
Cytoplasmic Side
Associated With Forming But Not Mature Clathrin-Coated Vesicles
The Recruitment To Coated-Pits Precede The One Of Clathrin And The Adaptor Protein Complex Ap-2
It May Also Dynamically Associate With Golgi/Tgn Membranes
Alternative Antibody Names Anti-F-Bar Domain Only Protein 1 antibody
Anti-FCHO1 antibody
Anti-KIAA0290 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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