产品详情
简单介绍：
Anti-FKBP1A antibody (29-108) [S5MR] (STJ11101375)
详情介绍：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-FKBP12 (29-108) is suitable for use in Western Blot research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S5MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FKBP1A |
| Gene ID: | 2280 |
| Uniprot ID: | FKB1A_HUMAN |
| Immunogen Region: | 29-108 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 29-108 of human FKBP12 (P62942). |
| Immunogen Sequence: | GMLEDGKKFDSSRDRNKPFK FMLGKQEVIRGWEEGVAQMS VGQRAKLTISPDYAYGATGH PGIIPPHATLVFDVELLKLE |
| Function | Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a Ppiase Fkbp1a 12 Kda Fk506-Binding Protein 12 Kda Fkbp Fkbp-12 Calstabin-1 Fk506-Binding Protein 1a Fkbp-1a Immunophilin Fkbp12 Rotamase |
| Database Links | Reactome: R-HSA-166208 Reactome: R-HSA-2025928 Reactome: R-HSA-2173789 Reactome: R-HSA-2173791 Reactome: R-HSA-3656535 Reactome: R-HSA-9679191 Reactome: R-HSA-9692916 |
| Cellular Localisation | Cytoplasm Cytosol Sarcoplasmic Reticulum Membrane Peripheral Membrane Protein Cytoplasmic Side |
| Alternative Antibody Names | Anti-Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a antibody Anti-Ppiase Fkbp1a antibody Anti-12 Kda Fk506-Binding Protein antibody Anti-12 Kda Fkbp antibody Anti-Fkbp-12 antibody Anti-Calstabin-1 antibody Anti-Fk506-Binding Protein 1a antibody Anti-Fkbp-1a antibody Anti-Immunophilin Fkbp12 antibody Anti-Rotamase antibody Anti-FKBP1A antibody Anti-FKBP1 antibody Anti-FKBP12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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