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  • 产品名称：Anti-FRK antibody (2-300 aa) [1A8H2C12] (STJ98353)

  • 产品型号：STJ98353
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-FRK antibody (2-300 aa) [1A8H2C12] (STJ98353)
详情介绍：
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Tyrosine-protein kinase FRK (2-300 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 1A8H2C12
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FRK
Gene ID: 2444
Uniprot ID: FRK_HUMAN
Immunogen Region: 2-300 aa
Specificity: Rak Monoclonal Antibody detects endogenous levels of Rak protein.
Immunogen: Purified recombinant fragment of Rak (aa2-300) expressed in E. Coli.
Function Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Protein Name Tyrosine-Protein Kinase Frk
Fyn-Related Kinase
Nuclear Tyrosine Protein Kinase Rak
Protein-Tyrosine Kinase 5
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8948751
Cellular Localisation Cytoplasm
Nucleus
Predominantly Found In The Nucleus
With A Small Fraction Found In The Cell Periphery
Alternative Antibody Names Anti-Tyrosine-Protein Kinase Frk antibody
Anti-Fyn-Related Kinase antibody
Anti-Nuclear Tyrosine Protein Kinase Rak antibody
Anti-Protein-Tyrosine Kinase 5 antibody
Anti-FRK antibody
Anti-PTK5 antibody
Anti-RAK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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